Read e-book online LC/MS Applications in Drug Development (Wiley Series on Mass PDF

By Mike S. Lee

ISBN-10: 0471405205

ISBN-13: 9780471405207

Breakthroughs in combinatorial chemistry and molecular biology, in addition to an total pattern towards sped up improvement, suggest the speed of pattern new release now some distance exceeds the speed of pattern research within the pursuit of manufacturing new and higher prescription drugs. LC/MS is an analytical device that is helping the researcher establish the main promising pattern early within the choice procedure, successfully making a shortcut to discovering new medicines. This publication is the 1st to explain LC/MS functions in the context of drug improvement, together with the invention, preclinical, scientific, and production phases.
as well as the thorough technical research of this software, LC/MS functions in Drug Development offers viewpoint at the major alterations in ideas for pharmaceutical research. A strategy review of drug improvement from an analytical viewpoint is supplied besides crucial info required to effectively carry a drug to industry. The incorporation of LC/MS is illustrated from goal to product. Chapters relating the invention method itself comprise:

  • Proteomics
  • Glycoprotein Mapping
  • Natural items Dereplication
  • Lead id Screening
  • Open-Access LC/MS
  • In Vitro Drug Screening

Written for either the analytical chemist who makes use of LC/MS functions and the pharmaceutical scientist who works with the medicine they produce, LC/MS functions in Drug Development is the superior reference at the subject.

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LC/MS Applications in Drug Development (Wiley Series on Mass Spectrometry) by Mike S. Lee


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