By Micaela Reddy,R. S. Yang,Melvin E. Andersen,Harvey J. Clewell III
ISBN-10: 0471478148
ISBN-13: 9780471478140
Physiologically-based pharmacokinetic (PBPK) modeling is changing into more and more vital in human overall healthiness possibility checks and in assisting pharmacodynamic modeling for poisonous responses. prepared by means of periods of compounds and modeling reasons so clients can quick entry info, this can be the 1st finished reference of its kind.
This booklet provides an summary of the underlying ideas of PBPK version improvement. Then it presents a compendium of PBPK modeling info, together with historic improvement, particular modeling demanding situations, and present practices for:
* Halogenated Alkanes
* Halogenated Alkenes
* Alkene and fragrant Compounds
* Reactive Vapors within the Nasal Cavity
* Alkanes, Oxyhydrocarbons, and similar Compounds
* insecticides and protracted natural Pollutants
* Dioxin and similar Compounds
* Metals and Inorganic Compounds
* Drugs
* Antineoplastic Agents
* Perinatal Transfer
* Mixtures
* Dermal publicity Models
as well as pinpointing particular details, readers can discover diversified modeling ideas and purposes. An authoritative reference for toxicologists, ecotoxicologists, threat assessors, regulators, pharmacologists, pharmacists, and graduate scholars in pharmacokinetics and toxicology, Physiologically-Based Pharmacokinetic Modeling compiles info from leaders within the box and discusses destiny instructions for PBPK modeling.
Read or Download Physiologically Based Pharmacokinetic Modeling: Science and Applications PDF
Best industrial & technical chemistry books
Refineries mustn't ever in basic terms adapt to evolving environmental rules for cleanser product necessities and processing, but in addition locate how you can meet the expanding call for for petroleum products,particularly for liquid fuels and petrochemical feedstocks. The Chemistry and know-how of Petroleum, Fourth version bargains a twenty first century point of view at the improvement of petroleum refining applied sciences.
This is often the 1st publication within the box to target those features, supplying super priceless info unavailable in other places for an individual looking the sensible software of microreactor expertise in preparative chemistry. the themes coated department out in 3 varied instructions. to start with, the information worthy for the preparative chemistry about the impression of the so-called microeffects at the response method and on mass and warmth move in addition to the skin phenomena are supplied intimately.
Get Soluble Bio-based Substances Isolated From Urban Wastes: PDF
This short provides a precis of the soluble bio-based elements (SBO) box. city bio-wastes of differing compositions and ageing stipulations characterize a promising resource of soluble bio-based components (SBO), very likely capable of practice as chemical auxiliaries for purposes within the chemical and in environmental remediation.
Smart Composite Coatings and Membranes: Transport, by Maria Fatima Montemor PDF
Clever Composite Coatings and Membranes: delivery, Structural, Environmental and effort purposes presents the most recent info at the bring up admired for brand new clever fabrics for a big selection of alternative technological purposes. The ebook comprehensively experiences the most recent advancements in clever composite fabrics used as membranes, boundaries, and coatings, with a unique specialize in corrosion security, transportation, constitution, and the wide variety of purposes.
- Transport Phenomena Fundamentals, Third Edition (Chemical Industries)
- Metal-Induced Crystallization: Fundamentals and Applications
- Membranen: Grundlagen, Verfahren und Industrielle Anwendungen (German Edition)
- The Chemistry and Technology of Petroleum, Third Edition, Revised and Expanded (Chemical Industries)
- Handbook of Dehumidification Technology
Additional info for Physiologically Based Pharmacokinetic Modeling: Science and Applications
Example text
Physiologically Based Pharmacokinetic Modeling: Science and Applications by Micaela Reddy,R. S. Yang,Melvin E. Andersen,Harvey J. Clewell III
by Anthony
4.3