Robert C. Smart,Ernest Hodgson's Molecular and Biochemical Toxicology PDF

Over the process thirty years and 3 variants, Introduction to Biochemical Toxicology has been an enormous resource for assurance of the continuing quest to outline the biochemical, mobile, and molecular occasions brought on via toxicants on the mobile and organismic degrees. Now, because the ideas and strategies of molecular and mobile biology in addition to genomic sciences play an ever expanding function in mechanistic toxicology, major adjustments were made to the ebook, leading to this crucial new edition-now titled Molecular and Biochemical Toxicology, Fourth Edition.

Much greater than an introductory textual content, this significant re-creation has been thoroughly revised to supply well timed and thorough insurance of the underlying biochemical, molecular, and mobile mechanisms during which toxicants produce their antagonistic results. Toxicological matters are coated from the molecule to the phone to the organ point. advanced equipment utilized in toxicology also are defined in an easy, easy-to-understand type. extra gains of this re-creation include:

• New chapters that discover the interface among toxicology and genomic sciences, together with: bioinformatics, proteomics, metabolomics, and toxicogenomics
• Increased emphasis on constitution, mechanism, and law of xenobiotic metabolizing enzymes, toxicogenetics, and xenobiotic transporters
• Additional new chapters on: molecular epidemiology and genetic susceptibility, DNA harm and mutagenesis, DNA fix, mechanisms of phone dying, mitochondrial disorder, metals, reproductive toxicology, developmental toxicology, and reactive oxygen/metabolites and toxicity

Molecular and Biochemical Toxicology, Fourth variation publications graduate scholars, toxicologists, and environmental well-being execs throughout the ideas of molecular and biochemical toxicology and the complicated mechanisms of toxicity. no matter if it is utilized in the school room or in undefined, learn, or academia, this ebook is vital for somebody drawn to knowing the molecular mechanisms by which toxicants produce antagonistic effects.